Multiplexing information flow through dynamic signalling systems
نویسندگان
چکیده
منابع مشابه
Systems biology. Accurate information transmission through dynamic biochemical signaling networks.
Stochasticity inherent to biochemical reactions (intrinsic noise) and variability in cellular states (extrinsic noise) degrade information transmitted through signaling networks. We analyzed the ability of temporal signal modulation--that is, dynamics--to reduce noise-induced information loss. In the extracellular signal-regulated kinase (ERK), calcium (Ca(2+)), and nuclear factor kappa-B (NF-κ...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2020
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1008076